Inherent Challenges

Every Surgery is Risky Business

There is no getting around it - there are inherent risks to surgery. The majority of deoxygenation problems are not caused by treatment error; they are inherent risks of standard treatment tools and techniques and/or the patient's own physiological condition. In fact, a study of nearly 12,000 cardiac surgery patients showed that 75% of strokes occur among the 90% of patients classified as low- to medium-risk pre-operatively1. This demonstrates that current techniques to identify vulnerable patients and methods to protect them from complications have room for improvement. Here are examples of treatment and patient physiology-related risks that can undermine good outcomes:

Treatment-Associated Risks:
  • Positioning or shifting of cannulas
  • Position of the head or neck
  • Clamping of arteries
  • Lifting of the heart
  • Perfusion rates and methods
  • Anesthesia dosage and methods
  • Warming and cooling of patients
  • Closing the chest incision (most relevant in pediatric surgery)
  • Loss of regional blood flow due to blockage or clotting
  • ECMO or ventilator treatment

Patient Physiology-Associated Risks:
  • Incomplete Circle of Willis
  • Level of reactivity to carbon dioxide
  • Degree of cerebral autoregulation (i.e., the ability or inability to automatically adjust cerebral blood flow as pressure drops)
  • Congenital heart malformations
  • Swelling of tissues or accumulation of fluids

Footnote:
1. Likosky et al. Ann Thorac Surg 2003;76:428-35.